Tests have been carried out on over 30 humans. In each case the tumor masses disappeared. Also all pains and effects associated with cancer disappeared within 12 to 36 hr; the more chemotherapy and morphine the patient had taken, the longer the withdrawal period. Studies of the food intake in areas where the incidences of cancer are very low showed that it met the requirements for the high pH therapy.

There was an impressive 50% recovery of various cancers, i.e., cancer of unknown primary, breast, colon, prostate, pancrease, lung, liver, lymphoma, ewing sarcoma of the pelvis and adeno-cancer of the gallbladder, by the Cs-therapy employed. A consistent finding in these patients was the disappearance of pain within the initial 3 days of Cs-treatment. The small number of autopsies made showed the absence of cancer cells in most cases and the clinical impression indicates a remarkably successful outcome of treatment.

- Supra-nutritional selenium supplementation has emerged as an attractive new approach to intervene in a range of human cancers.
- However, scanty information is currently available on molecular mechanisms underlying selenium's anticancer action. 
- Since majority of the early-stage human prostate cancers bear functional p53 gene (p53+/+), our findings indicate that the anticancer action of selenium may involve transactivation of p53 as a potential mechanism.
- Results suggest that selenite may be useful not only for prevention but also for treatment of human prostate cancer.

- Selenium (Se) is an essential dietary component for animals including humans and is regarded as a protective agent against cancer.
- Several mechanisms, such as antioxidant protection, inhibition of tumor cell growth and effect on DNA repair have all been proposed.
- The cancer-preventing activity of Se was demonstrated in majority of the epidemiological studies.
- Moreover, recent studies suggest that Se has a potential to be used not only in cancer prevention but also in cancer treatment.
- In combating cancer cells, Se acts as pro-oxidant rather than antioxidant, inducing apoptosis through the generation of oxidative stress.
- Thus, inorganic Se compound, sodium selenite (SeL), due to its pro-oxidant character, represents a promising alternative for cancer therapy.

- Selenium is a promising chemopreventive agent for prostate cancer, possibly via an induction of apoptosis.
- Earlier studies have shown that selenite induces DNA single strand breaks (SSBs) and reactive oxygen species (ROS).
- Results support the sustaining of ROS superoxide production to lead to efficient caspase-mediated apoptosis by selenite

Sodium selenite (Se) is known to induce diverse stress responses in malignant cells which may lead to various types of cell death including apoptosis and / or autophagy.

Selenite can reduce the nephro-toxicity of cisplatin. The protection correlates with higher levels of selenium in the kidney (about eight times) and with higher levels of glutathione in the kidney, both compared to tumors.

Selenium, administered intravenously or intraperitoneally, has been shown to provided protection against nephr-otoxicity in rats.